Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/_YpNO3bhylE/130726074238.htm
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/_YpNO3bhylE/130726074238.htm
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All Critics (73) | Top Critics (32) | Fresh (64) | Rotten (9)
The film is touching, filled with taste and care, but not enough to avoid being coy and sentimental.
On the surface, this indie does sound like standard-issue material, but its dynamics are far more complex than its simple exterior.
What Maisie Knew gives the audience a ground-eye view of its mesmerizing title character, a plucky, charismatic New Yorker who navigates downtown bars and building lobbies with the street savvy of a pro.
The result is a film that deeply engages us on multiple levels. Not only do we wonder what Maisie knows and how she knows it, we want to get this seedling to a place where she won't have to be transplanted every day.
It's a study of human nature, not at its worst, but at its most typically pathetic, and it goes to show that the more things don't change, the more they stay lousy.
Intimate, unnerving and entirely addictive.
This is a film that deals in subtle details, and its value lies in the way the filmmakers draw out small moments of surprise or truth from the familiar scenario.
It's far from the first story of a child dealing with the consequences of parental break-up -- but it may be one of the best.
The worthwhile subject matter becomes trivialized.
A wonderful modernized re-telling of the 1897 Henry James short story.
It's an intimate, well-acted and nuanced film that provides a fresh angle on an all-too-familiar struggle.
Onata Aprile is never showy and always authentic, a rare find in a child actor. In fact, she is one of the most self-possessed actors I've seen of any age.
A movie that's much easier to admire than to actually enjoy, no matter how well done or acted.
Onata Aprile's short career should blossom as people react to her subtle performance here.
Despite the big-name adults around her, it's the unknown Onata Aprile who is the star of this movie.
Gazing on Maisie, you want to know what she knows. That you can't is at once your dilemma and your opportunity, what adults must engage in order to be adults.
Despite a sensitive, mature performance from Onata Aprile as Maisie, the girl remains withdrawn and opaque throughout. In telling this sad story from her perspective, it never quite plugs in to what Maisie felt.
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Source: http://www.rottentomatoes.com/m/what_maisie_knew_2012/
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HTC's just pulled back the proverbial curtains on the Butterfly s at its Taiwan launch event. It'll arrive boasting a familiar-sounding 5-inch 1080p display, front-facing BoomSound stereo speakers and Sense 5 as expected. When it comes to internals, the Butterfly s runs Android Jelly Bean on a quad-core 1.9GHz Snapdragon 600 (faster than the HTC One), an impressive 3,200mAh battery, quad-band HSPA/WCDMA radio, 2GB of RAM and 16GB of built-in storage, expandable once again through microSD. As for imaging, alongside that primary UltraPixel camera and Zoe software features, there's a 2.1-megapixel wide-angle shooter on the front. It's currently scheduled for a release in July in Taiwan, accompanied by a NT $22,900 (roughly $766) price tag, but no word when (or even if) it'll reach foreign shores.
Update: Our Chinese sister site just spent some hands-on time with the device. Check out their first impressions right here. And look! A gallery right below!
Filed under: Cellphones, Mobile, HTC
Source: Engadget Chinese
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By Daily Mail Reporter
PUBLISHED: 06:42 EST, 19 June 2013 | UPDATED: 08:49 EST, 19 June 2013
The fashion wars on The X Factor have truly begun.
And sizzling judge Nicole Scherzinger has crushed all competition by rocking up to the latest auditions in London in an incredibly sexy outfit.
The former Pussycat Doll, 34, got lustful singing hopefuls in a frenzy of excitement by wearing a tiny trench coat and little else as she arrived at the ExCeL Centre.
Sizzling Scherzy: Nicole Scherzinger stood out from her fellow judges as The X Factor auditions arrived in London on Wednesday
Injecting a high dosage of sex appeal into the judging panel, Nicole smouldered in a leather trench which she teamed with a sexy pair of red and gold heels.
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The Wet singer certainly made for a sexy sight as she prepared to listen to countless auditionees wail through the beginning stage of the competition.
'I had so much fun and such a great experience on the show last year ? it far exceeded all my expectations!' the star said when it was confirmed she would return to the show after her category won last year's show.
She smoulders! The former Pussycat Doll was just stunning as she took to the X Factor red carpet
What's beneath the coat? Nicole's teasing outfit allows the imagination to believe that she is wearing nothing under her coat
Hello everyone: Nicole arrived in her private car - and it would seem she had been reading OK! and GQ magazines during her commute
'I always give 110% to all I do and I put everything else on hold to focus on X Factor and supporting my Scherzy boys,' she continued.
'This year, now that I?ve worked out doing my new music and the show together, I am so excited to get back to the UK, my second home, and get stuck into X Factor 2013!'
Fellow female judge Sharon Osbourne looked like she may have raided one of husband Ozzy's outfits for this round of auditions.
Diamonds and pearls: The singer was joined by a guest for a quick photo on the red carpet
Will they be performing? A pearly king and queen flank Ms Scherzinger
She's back: Sharon Osbourne has made a triumphant return to The X Factor judging panel
Standing out in the crowd, the 60-year-old music expert gave a bit of Goth glam to the X Factor red carpet in a black suit with pointed orange heels.
'I couldn?t be happier about coming back for the 10th anniversary of X factor,' Sharon said when it was revealed she would be making a triumphant return to the judging panel.
'I can?t wait to give Gary Barlow a big hug, sit next to the gorgeous Nicole, and of course throw water on dear Louis. Yay!'
X-cited? Sharon has been quite vocal about how much she is looking forward to returning to judge on the singing show
Good X-ample: Sharon is regarded by many as one of the best business women in the music industry
Ready for more: Sharon can't wait to sit with Gary and Nicole - and douse Louis with water
While Sharon is thrilled to be returning to The X Factor, her husband Ozzy has recently opened up about his own TV career - making suggestion that he regrets appearing on The Osbournes on MTV earlier this century.
'That was a period of my career that I?m f***ing glad is gone,? the 64-year-old told Classic Rock on his reality TV days.
?Sharon?s turned into this television person now. And she?s great. But she?s always saying to me: ?You are coming to the show, aren?t you?? And I?m going. ?No! I f***ing hate doing TV!? I didn?t start off playing music to be the fucking weatherman".'
Hey handsome: Gary Barlow is back for a third round of X Factor fun
Gary Barlow is returning for his third round of The X Factor and will continue to serve as head judge on the hit ITV show - looking hunky for this round of auditions in a deep navy blue polo shirt, black jeans, and well worn boots.
'It's great to be back for the 10-year anniversary of X Factor and my third year with the show,' he said earlier this year.
'This year is looking to be our best yet! To have a winner like James Arthur last year was a big game changer; I really hope that his authenticity and credibility will attract acts of a similar talent this series and I'm very excited about that.'
What a hunk: Gary looked highly desirable even in his casual wear as he headed to watch some potentially awful auditions
Someone is a fan: A pearly queen went in for a hug from the Take That mega star
And of course no X Factor year would be complete without Louis Walsh.
'I'm back with a vengeance!' the 60-year-old said earlier this year - the only judge to have survived every season of the show to remain on the panel (excluding a brief disappearance in series 3)
'Ten years on and I'm just as thrilled to be involved in the best show on TV and even more delighted to be re-united with original judge Sharon Osbourne. Let the fun and games commence!'
Lou Lou is back: Mr Walsh is the only X Factor judge to have appeared on every series of the show
Is that waterproof? Louis looked delightful in a purple hue blazer - but he might need to duck if Sharon throws water at him
And of course sister show The Xtra Factor is capturing all the fun and scandal that can't make it onto the main show.
Co-hosts Caroline Flack, 33, and Matt Richardson, 22, were on hand to talk to contestants and keep the judges in check.
Caroline looked a delight in a pair of black shorts, a corresponding black top, and white blazer.
Flack in Straps: Caroline wore strappy shoes, shorts, a T-shirt and a cream blazer and looked lovely
Change up: Caroline is back to present The Xtra Factor, but Ollie Murs is not
She also wore cute black strappy shoes and had a bright lip and her hair slightly disheveled and sexy.
Plucked from obscurity, Xtra Factor co-host Matt is on course to be a new TV heartthrob.
Rocking up to the audition, the comedian looked dapper in a light blue blazer, black jeans, white shirt and white shoes - suggesting he's already got his wardrobe down for the competition that will see him on screens from August to Christmas.
New on-screen couple: Caroline is instead joined by up-and-coming comedian Matt Richardson who scrubbed up well for the London auditions
Xtra hot: Flackers and Matt will be fronting the sister show all the way to Christmas
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A petition launched last weekend on the White House?s ?We the People? website calls upon President Barack Obama to issue a decree forbidding the teaching of intelligent design theories in school settings.
The petition, created by someone with the initials A.J. in Vienna, Va. asks the Obama administration to ?[b]an Creationism and Intelligent Design in the science classroom as federal law.?
?Since Darwin?s groundbreaking theory of Evolution by Natural Selection, scientists all around the world have found monumental amounts of evidence in favor of the theory, now treated as scientific fact by 99.9% of all scientists,? the petition reads.
?However, even after 150 years after the establishment of evolution, some schools across the US are ?teaching the controversy,? including Creationism and Intelligent Design,? the petitioner continues. ?Both of these so-called ?theories? have no basis in scientific fact, and have absolutely zero evidence pointing towards these conjectures. These types of loopholes in our education are partially to blame for our dangerously low student performances in math and science.
?Therefore, we petition the Obama Adminstration [sic] to ban the teachings of these conjectures that contradict Evolution.?
The petitioner does not cite a source for statistic concerning the percentage of scientists who now treat evolution as a fact. Similarly, the connection between teaching creationism in science and poor performance in math goes unexplained.
It?s also not clear which executive power Obama could use to implement such a ban in the absence of a bill passed by both the House and the Senate.
Whatever the case, the bill has seen a steady stream of supporters. The total number of signatures has climbed over 7,600 as of late Tuesday night. The petition still needs over 92,000 signatures to reach the goal of 100,000 signatories.
The ?We The People? website, which was the brainchild of the director of the White House office of digital strategy, requires petitions to achieve at least 100,000 signatures before they receive an official White House response. The magic number used to be a mere 25,000.
The fourfold increase in required signatures came in response to petitions calling for things such as the construction of a Star Wars-inspired orbital death cannon that previously reached the 25,000 signatory threshold. (RELATED: White House staff: Our petition website sure is dumb, huh?)
Follow Eric on Twitter?and send education-related story tips to?erico@dailycaller.com.
Join the conversation on The Daily Caller
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White house petition wants Obama to ban creationism, intelligent design in schools
Community college professor allegedly tells students: support gay rights or else
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Journalist Michael Hastings killed in fiery L.A. crash
Competing polls produce mixed views on oil and gas development
Source: http://news.yahoo.com/white-house-petition-wants-obama-ban-creationism-intelligent-121604634.html
A Hastings family are reeling from a suspected arson attack just days after they escaped a house fire.
Emergency services were called to the Fitzroy Ave villa about 4am yesterday.
Senior station officer Kerry Harford, of the Hastings fire service, said crews arrived "in the nick of time" as part of the house was well ablaze with flames coming out a window. Firefighters confined the fire to the bedroom it started in.
It was being treated as suspicious because of signs of a break-in, Mr Harford said. Police are investigating.
Just days earlier, Vanessa Abraham-Smith had jumped out of her window, with her 10-year-old son and pet dog, escaping her burning bedroom.
A smoke alarm woke the mother about 4am last Thursday. Once out of her smoke-filled room, she got her three older children out the back of the house and rang emergency services. A damaged electrical lead caused the fire. The family had since been staying in a motel.
Abraham-Smith was shocked that someone could have purposely set her home alight.
"You laugh about it one moment and cry the next."
She had been on a "bit of a high", grateful that the family had got through the first fire. However, the second blaze brought disbelief, shock and anger.
"It looks like someone has broken in and done it for a bit of fun."
The latest fire had caused a lot more smoke and water damage to the home.
While it was "just a building", she was more upset that it was a suspected arson, she said.
"It's our home, we raised our babies in it for the last 15 years, now it's almost quite scary that things could have gone so wrong."
The family would stay at the motel longer while they filed a second insurance claim and worked out if they could return to their home.
- ? Fairfax NZ News
Source: http://www.stuff.co.nz/national/crime/8807198/Arson-attack-on-family-days-after-house-blaze
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Typically, knowledge-intensive processes are often only slightly structured and may not be completely captured by common business process models. Variations or divergence from structured, pre-defined reference models are common, due to autonomous user decisions and to unpredictable, emergent events and contextual changes that make the structure of the process significantly less rigid. The explicit flow of control may be driven and implicitly determined by the user's decision making or by contextual conditions, and it may be coupled with undesigned and unforeseen alternative activities and process fragments, dynamically determined at run-time. In the worst case, there is no pre-defined view of the knowledge-intensive process, and tasks are mainly discovered as the process unfolds.
In recent years, the increasing demand in effective solutions for knowledge-intensive processes has been reflected in the arising of various approaches (such as declarative and object-centric processes, artifact-centric systems, and adaptive case management) that emphasize how the integration of rules, data, control flow and user decisions may support the specification, analysis and enactment of flexible, knowledge-intensive business processes. From the foundational and practical viewpoint, the purpose of integrating such aspects with traditional business process management is a challenging, still largely open issue, which requires to reconsider the role of each process component together with the ways it interacts with the other components, and ultimately to reshape the entire process life-cycle.
The main focus of this workshop is to discuss novel and ongoing approaches, techniques and tools whose distinctive feature relies in the interplay between data, users and control flow aspects, to the aim of defining and understanding the knowledge dimension for business processes. We invite researchers from the fields of service-oriented computing, business process management, data management, artificial intelligence, knowledge representation and management to submit papers on the following aspects (not exclusive):
Modeling languages, notations and methods for knowledge representation and management in business processes and services
Variability and adaptability of business process models for knowledge-intensive tasks through automatic techniques
Resource management for knowledge-intensive business process modeling and support
User-oriented aspects of knowledge-intensive business processes and services
Declarative approaches for knowledge-intensive business processes
Verification, analysis and validation of knowledge-intensive business processes and services
Dynamic configuration; modeling by knowledge reuse
Run-time verification and monitoring
Knowledge-intensive business process/service support architectures and platforms
Machine learning for business process mining and monitoring
Artifact-centric business processes
Adaptive Case Management
Object-aware approaches for business process management
Case studies, empirical evaluations and experimentations
Source: http://www.wikicfp.com/cfp/servlet/event.showcfp?eventid=31323©ownerid=2
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LOS ANGELES (AP) ? Los Angeles police say "Curb Your Enthusiasm" actor and comedian Jeff Garlin has been arrested on a felony vandalism charge after a dispute with another motorist over a parking space.
Police Sgt. Harry Rosenfeld says the 51-year-old actor was arrested for allegedly smashing the windows of the other person's car. Rosenfeld says officers arrested Garlin in Studio City on Saturday.
Garlin was jailed on $20,000 bail. It wasn't clear from the Los Angeles County Sheriff's Department's website if he had been released. Garlin's publicists didn't immediately respond to phone and email messages Sunday.
Garlin played Larry David's friend and manager on "Curb Your Enthusiasm" and was the show's co-executive producer. He's also appeared frequently on "Arrested Development" and numerous other television shows.
TMZ first reported his arrest.
Source: http://news.yahoo.com/curb-enthusiasm-actor-jeff-garlin-arrested-222611087.html
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BELFAST, Northern Ireland (AP) ? President Barack Obama declared peace in Northern Ireland a "blueprint" for those living amid conflict around the world, while acknowledging that the calm between Catholics and Protestants will face further tests. Summoning young people to take responsibility for their country's future, Obama warned there is "more to lose now than there's ever been."
"The terms of peace may be negotiated by political leaders, but the fate of peace is up to each of us," Obama said Monday during remarks at Belfast's Waterfront Hall. The glass-fronted building would never have been built during the city's long era of car bombs.
Obama arrived in Northern Ireland Monday morning after an overnight flight from Washington. Following his remarks in Belfast, he was bound for a lakeside golf resort in Enneskillen for meetings with other leaders of the Group of 8 industrial nations on Syria, trade and counterterrorism. Later Monday, Obama was meeting one-on-one with Russian President Vladimir Putin, British Prime Minister David Cameron and Italian Prime Minister Enrico Letta.
Cameron selected Enniskillen as the site of this year's meeting as a way to highlight Northern Ireland's ability to leave behind a four-decade conflict that claimed 3,700 lives.
Significant progress has been made in the 15 years since the U.S.-brokered Good Friday Accords, including a Catholic-Protestant government and the disarmament of the IRA and outlawed Protestant groups responsible for most of the 3,700 death toll. But tearing down Belfast's nearly 100 "peace lines" ? barricades of brick, steel and barbed wire that divide neighborhoods, roads and even one Belfast playground ? is still seen by many as too dangerous. Obama cited that playground in his speech, lauding an activist whose work led to the opening of a pedestrian gate in the fence.
Acknowledging the reality of a sometimes-fragile peace, Obama recalled the Omagh bombings that killed 29 people and injured hundreds more. It was the deadliest attack of the entire conflict and occurred after the Good Friday deal.
Peace will be tested again, Obama said.
"Whenever your peace is attacked, you will have to choose whether to respond with the same bravery that you've summoned so far or whether you succumb to the worst instincts, those impulses that kept this great land divided for too long. You'll have to choose whether to keep going forward, not backward," he said.
Last month, the Catholic and Protestant leaders of Northern Ireland's unity government announced a bold but detail-free plan to dismantle all peace lines by 2023. British Prime Minister David Cameron formally backed the goal Friday, and Obama followed with his own endorsement Monday.
The president specifically endorsed an end to segregated housing and schools, calling it an essential element of lasting peace.
"If towns remain divided ? if Catholics have their schools and buildings, and Protestants have theirs, if we can't see ourselves in one another, if fear or resentment are allowed to harden ? that too encourages division. It discourages cooperation," Obama said.
One symbol of that effort to end the segregation was on display as Obama spoke to an audience that brought together students from both faiths, effectively integrating Northern Ireland's schoolchildren if just for a morning.
Drawing on America's own imperfect battle with segregation, Obama recalled how a century after the U.S. Civil War, the nation he leads is still not fully united. His own parents ? a white woman from Kansas and a black man from Kenya ? would not have been able to marry in some states, Obama said, and he would have had a hard time casting a ballot, let alone running for office.
"But over time, laws changed, and hearts and minds changed, sometimes driven sometimes by courageous lawmakers, but more often driven by committed citizens," he said.
Though Obama did not specifically mention Syria, his remarks on Northern Ireland recalled the fierce conflict there that has so far resulted in 93,000 deaths. For those looking for a way out of conflict, Obama said Northern Ireland is "proof of what is possible."
Obama and other G-8 leaders were expected to discuss Syria Monday night over a working dinner. Obama will be looking to Britain and France to join him in sending weapons to the Syrian opposition.
Casting a shadow over the summit are new revelations by the Guardian newspaper that the British eavesdropping agency GCHQ repeatedly hacked into foreign diplomats' phones and emails when the U.K. hosted international conferences, including a 2009 Group of 20 summit in London. The report follows recent disclosures about the U.S. government's own surveillance programs and could lead to awkward conversation as the leaders open another international gathering that Britain is hosting.
Despite an agenda devoted to trade, economic growth and international tax issues, the G-8 will be eclipsed by discussions over how to address the two-year-old civil war in Syria and the decision by the United States to begin supplying rebels with military aid.
Obama's meeting with Russia's Putin later Monday will highlight the rift between their countries in addressing fierce fighting in Syria. While Putin has called for negotiated peace talks, he has not called for Syrian President Bashar Assad to leave power, and he remains one of Assad's strongest political and military allies.
In a likely preview of his discussions with Obama, Putin defended Russia's continuing supply of weapons to Assad's military in a meeting Sunday with Cameron, the British leader.
Putin said Russia was providing arms "to the legitimate government of Syria in full conformity with the norms of international law."
The White House is not expecting any breakthrough with Putin on Syria during Putin's meeting with Obama.
Obama is making his first visit to Northern Ireland, though he visited the neighboring Republic of Ireland in 2011. That trip included a public speech in the center of Dublin, as well as a stop in the village of Moneygall, where Obama's great-great-great grandfather was born. The president called that visit "magical."
First lady Michelle Obama and daughters Malia and Sasha, who also made the trip from Washington, were to spend Monday and Tuesday in Dublin while the president attended the G-8 summit. Later Tuesday, the first family departs for Germany, where the president will meet with Chancellor Angela Merkel and speak at the Brandenburg Gate.
___
Associated Press writer Julie Pace in Sligo, Ireland and Shawn Pogatchnik in Enneskillen, Northern Ireland contributed to this report.
Source: http://news.yahoo.com/obama-northern-ireland-peace-tested-090605238.html
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ENNISKILLEN, Northern Ireland (AP) ? Northern Ireland police commanders said Sunday they're optimistic that the G-8 summit will pass peacefully, with only 2,000 protesters expected to travel to the remote lakeside venue for the main demonstration.
About 7,000 officers, half of them imported from Britain, are providing security as leaders arrive for the two-day summit starting Monday at a golf resort on a peninsula near the town of Enniskillen.
Chief Constable Matt Baggott and his deputy overseeing G-8 security, Alistair Finlay, said they're expecting no violence and little participation by foreign protesters. They noted that police were surprised that they didn't have to make a single arrest during two anti-G-8 protests and a related outdoor concert Saturday in Belfast.
"We are quietly optimistic based on what we've seen yesterday that this could be the most successful G-8 conference," Baggott told reporters at the summit press center.
A range of socialist and anti-globalization groups plan to march Monday night from central Enniskillen to high steel fences preventing access to the Lough Erne resort as G-8 leaders hold a working dinner expected to focus on foreign policy disputes, particularly Syria.
Finlay's forces already have formed a security perimeter around the resort that includes several miles (kilometers) of coiled razor wire and boat-based police units.
Officers spent weeks training in England to face potential crowds exceeding 10,000, but Finlay said intelligence estimates put the expected number of protesters Monday night at just 2,000.
He said very few hard-core socialist protesters who targeted past G-8 summits in Europe had traveled to Northern Ireland from continental Europe. He said police believe many this time have traveled instead to Turkey to join anti-government demonstrations there.
Source: http://news.yahoo.com/n-ireland-police-chiefs-optimistic-peaceful-g-8-201829357.html
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NASA
NASA's latest astronaut candidates come from a variety of backgrounds. Half of them are women.
By Clara Moskowitz
Space.com
NASA has picked eight Americans, a mix of scientists and military pilots, to begin training for future space missions that may one day launch them all the way to Mars. The new class includes four men and four women who will join the 49 active astronauts at the agency's astronaut corps at the Johnson Space Center in Houston.
The new U.S. space travelers, which NASA unveiled Monday, could be part of the first crews to visit an asteroid or Mars, deep-space goals that NASA aims to explore. They could also be the first people to launch to space on a U.S.-built rocket since the era of the space shuttle, which ended in 2011.
In the nearer term, the new recruits could launch on Russian rockets to serve long-duration missions on the International Space Station, which is expected to operate until at least 2020. [7 Notable Space Shuttle Astronauts]
"These new space explorers asked to join NASA because they know we're doing big, bold things here ? developing missions to go farther into space than ever before," NASA Administrator Charles Bolden said in a statement. "They're excited about the science we're doing on the International Space Station and our plan to launch from U.S. soil to there on spacecraft built by American companies. And they're ready to help lead the first human mission to an asteroid and then on to Mars."
The new spaceflier hopefuls were selected from more than 6,000 applications ? the second-largest applicant pool NASA's ever had. With the new class being evenly split between men and women, it represents the largest percentage of female astronaut candidates in any new class. [Women in Space: A Space History Gallery]
The last new cohort of NASA astronauts was selected in 2009, and included nine new candidates. They officially graduated in November 2011, but none have flown to space yet. Michael Hopkins will be the first of that group to fly when he launches in September to the International Space Station.
The new candidates, NASA's 21st astronaut class, will report to the Johnson Space Center for training in August.
"This year we have selected eight highly qualified individuals who have demonstrated impressive strengths academically, operationally and physically," said Janet Kavandi, director of Flight Crew Operations at Johnson Space Center. "They have diverse backgrounds and skill sets that will contribute greatly to the existing astronaut corps. Based on their incredible experiences to date, I have every confidence that they will apply their combined expertise and talents to achieve great things for NASA and this country in the pursuit of human exploration."
The new candidates, as described by NASA, are:
NASA's astronaut corps began in 1959 with the announcement of the first seven astronauts, the Mercury Seven, who flew on the first U.S. space missions.
Follow Clara Moskowitz on Twitter and Google+. Follow us @Spacedotcom, Facebook and Google+. Original article on Space.com.
Copyright 2013 Space.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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If your world is feeling overwhelmingly and counter-productively materialistic it may be time to downsize your life and move into a hut. That's normal, right? And for all your sacrifice your minimalist hut can be built by celebrity architect
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June 14, 2013 ? Locating a car that's blowing its horn in heavy traffic, channel-hopping between football and a thriller on TV without losing the plot, and not forgetting the start of a sentence by the time we have read to the end -- we consider all of these to be normal everyday functions. They enable us to react to fast-changing circumstances and to carry out even complex activities correctly. For this to work, the neuron circuits in our brain have to be very flexible. Scientists working under the leadership of neurobiologists Nils Brose and Erwin Neher at the Max Planck Institutes of Experimental Medicine and Biophysical Chemistry in G?ttingen have now discovered an important molecular mechanism that turns neurons into true masters of adaptation.
Neurons communicate with each other by means of specialised cell-to-cell contacts called synapses. First, an emitting neuron is excited and discharges chemical messengers known as neurotransmitters. These signal molecules then reach the receiving cell and influence its activation state. The transmitter discharge process is highly complex and strongly regulated. Its protagonists are synaptic vesicles, small blisters surrounded by a membrane, which are loaded with neurotransmitters and release them by fusing with the cell membrane. In order to be able to respond to stimulation at any time by releasing transmitters, a neuron must have a certain amount of vesicles ready to go at each of its synapses. Brose has been studying the molecular foundations of this stockpiling for years.
The problem is not merely academic. "The number of immediately releasable vesicles at a synapse determines its reliability," explains Brose. "If there are too few and they are replenished too slowly, the corresponding synapse becomes tired very quickly in conditions of repeated activation. The opposite applies when a synapse can quickly top up its immediately available vesicles under pressure. In fact, such a synapse may even improve with constant activation."
This synaptic adaptability can be observed in practically all neurons. It is known as short-term plasticity and is indispensable for a large number of extremely important brain processes. Without it, we would not be able to localise sounds, mental maths would be impossible, and the speed and flexibility with which we can alter our behaviour and turn our attention to new goals would be lost.
Some years ago, Brose and his team discovered a protein with the cryptic name of Munc13. Not only is this protein indispensable for the replenishment of vesicles for immediate release at synapses; neuron activity regulates it in such a way that the fresh supply of vesicles can be adjusted in line with demand. This regulation occurs by means of a complex consisting of the signal protein calmodulin and calcium ions that build up in the synapses during intense neuron activity.
"Our earlier work on individual neurons in culture dishes showed that the calcium-calmodulin complex activates Munc13 and consequently ensures that immediately releasable vesicles are replenished faster," says Noa Lipstein, an Israeli guest scientist in Brose's lab. "But many colleagues were not convinced that this process also played a role in neurons in the intact brain."
So Lipstein and her Japanese colleague Takeshi Sakaba created a mutant mouse with genetically altered Munc13 proteins that could not be activated by calcium-calmodulin complexes. The two neurophysiologists first studied the effects of this genetic manipulation on synapses involved in the localisation of sound, which are typically activated several hundred times every second. "Our study shows that the sustained efficiency of synapses in intact neuron networks is critically dependent on the activation of Munc13 by calcium-calmodulin complexes," explains Lipstein.
The G?ttingen-based scientists are convinced of the significance of their study. After all, leading neuroscientists of the past described the calcium sensor responsible for synaptic short-term plasticity and its target protein as the Holy Grail. "I am confident that we have discovered a key molecular mechanism of short-term plasticity that plays a role in all synapses in the brain, and not only in cultivated neurons, as many colleagues believed," affirms Lipstein. And if she is, in fact, proved right about the interpretation of her findings, Munc13 could even be an ideal pharmacological target for drugs that influence brain function.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/pNO3ARGqRxk/130614082504.htm
WASHINGTON (AP) ? Efforts to curb global warming have quietly shifted as greenhouse gases inexorably rise.
The conversation is no longer solely about how to save the planet by cutting carbon emissions. It's becoming more about how to save ourselves from the warming planet's wild weather.
It was Mayor Michael Bloomberg's announcement last week of an ambitious plan to stave off New York City's rising seas with flood gates, levees and more that brought this transition into full focus.
After years of losing the fight against rising global emissions of heat-trapping gases, governments around the world are emphasizing what a U.N. Foundation scientific report calls "managing the unavoidable."
It's called adaptation and it's about as sexy but as necessary as insurance, experts say.
It's also a message that once was taboo among climate activists such as former Vice President Al Gore.
In his 1992 book "Earth in the Balance," Gore compared talk of adapting to climate change to laziness that would distract from necessary efforts.
But in his 2013 book "The Future," Gore writes bluntly: "I was wrong." He talks about how coping with rising seas and temperatures is just as important as trying to prevent global warming by cutting emissions.
Like Gore, governmental officials across the globe aren't saying everyone should just give up on efforts to reduce pollution. They're saying that as they work on curbing carbon, they also have to deal with a reality that's already here.
In March, President Barack Obama's science advisers sent him a list of recommendations on climate change. No. 1 on the list: "Focus on national preparedness for climate change."
"Whether you believe climate change is real or not is beside the point," New York's Bloomberg said in announcing his $20 billion adaptation plans. "The bottom line is: We can't run the risk."
On Monday, more than three dozen other municipal officials from across the country will go public with a nationwide effort to make their cities more resilient to natural disasters and the effects of man-made global warming.
"It's an insurance policy, which is investing in the future," Mayor Kevin Johnson of Sacramento, Calif., who is chairing the mayors' efforts, said in an interview Friday. "This is public safety. It's the long-term hazards that could impact a community."
Discussions about global warming are happening more often in mayors' offices than in Congress. The Obama administration and local governments are coming up with thousands of eye-glazing pages of climate change adaptation plans and talking about zoning, elevation, water system infrastructure, and most of all, risk.
"They can sit up there and not make any policies or changes, but we know we have to," Broward County, Fla., Mayor Kristin Jacobs said. "We know that we're going to be that first line of defense."
University of Michigan professor Rosina Bierbaum is a presidential science adviser who headed the adaptation section of the administration's new National Climate Assessment. "It's quite striking how much is going on at the municipal level," Bierbaum said. "Communities have to operate in real time. Everybody is struggling with a climate that is no longer the climate of the past."
Still, Bierbaum said, "Many of the other developed countries have gone way ahead of us in preparing for climate change. In many ways, the U.S. may be playing catch-up."
Hurricanes, smaller storms and floods have been a harsh teacher for South Florida, said Jacobs.
"Each time you get walloped, you stop and scratch your head ... and learn from it and make change," she said. "It helps if you've been walloped once or twice. I think it's easier to take action when everybody sees" the effect of climate change and are willing to talk about being prepared.
What Bloomberg announced for New York is reasonable for a wealthy city with lots of people and lots of expensive property and infrastructure to protect, said S. Jeffress Williams, a University of Hawaii geophysicist who used to be the expert on sea level rise for the U.S. Geological Survey. But for other coasts in the United States and especially elsewhere in the poorer world, he said, "it's not so easy to adapt."
Rich nations have pledged, but not yet provided, $100 billion a year to help poor nations adapt to global warming and cut their emissions. But the $20 billion cost for New York City's efforts shows the money won't go far in helping poorer cities adapt, said Brandon Wu of the nonprofit ActionAid.
At U.N. climate talks in Germany this past week, Ronald Jumeau, a delegate from the Seychelles, said developing countries have noted the more than $50 billion in relief that U.S. states in the Northeast got for Superstorm Sandy.
That's a large amount "for one storm in three states. At the same time, the Philippines was hit by its 15th storm in the same year," Jumeau said. "It puts things in context."
For poorer cities in the U.S., what makes sense is to buy out property owners, relocate homes and businesses and convert vulnerable sea shores to parks so that when storms hit "it's not a big deal," Williams said. "I think we'll see more and more communities make that decision largely because of the cost involved in trying to adapt to what's coming."
Jacobs, the mayor from South Florida, says that either people will move "or they will rehab their homes so that they can have a higher elevation. Already, in the Keys, you see houses that are up on stilts. So is that where we're going? At some point, we're going to have to start looking at real changes."
It's not just rising seas.
Sacramento has to deal with devastating droughts as well as the threat of flooding. It has a levee system so delicate that only New Orleans has it worse, said Johnson, the California capital's mayor.
The temperature in Sacramento was 110 this past week. After previous heat waves, cities such as Chicago, Philadelphia and Washington, D.C., have come up with cooling centers and green roofs that reduce the urban heat island affect.
Jacobs said cities from Miami to Virginia Beach, Va., are coping with mundane efforts: changes in zoning and building codes, raising the elevation of roads and runways, moving and hardening infrastructure. None of it grabs headlines, but "the sexiness is ... in the results," she said.
For decades, scientists referenced average temperatures when they talked about global warming. Only recently have they focused intensely on extreme and costly weather, encouraged by the insurance industry which has suffered high losses, Bierbaum said.
In 2012, weather disasters ? not necessarily all tied to climate change ? caused $110 billion in damage to the United States, which was the second highest total since 1980, the National Oceanic and Atmospheric Administration said last week.
Now officials are merging efforts by emergency managers to prepare for natural disasters with those of officials focused on climate change. That greatly lessens the political debate about human-caused global warming, said University of Colorado science and disaster policy professor Roger Pielke Jr.
It also makes the issue more local than national or international.
"If you keep the discussion focused on impacts ... I think it's pretty easy to get people from all political persuasions," said Pielke, who often has clashed with environmentalists over global warming. "It's insurance. The good news is that we know insurance is going to pay off again."
Describing these measures as resiliency and changing the way people talk about it make it more palatable than calling it climate change, said Hadi Dowlatabadi, a University of British Columbia climate scientist.
"It's called a no-regrets strategy," Dowlatabadi said. "It's all branding."
All that, experts say, is essentially taking some of the heat out of the global warming debate.
___
Associated Press writers Karl A. Ritter in Bonn, Germany, Jennifer Peltz in New York and Tony Winton in Miami contributed to this report.
___
Online:
Federal government's National Climate Assessment chapter on adaptation: http://1.usa.gov/154qUGs
The national mayors' efforts to promote adaptation: http://www.resilientamerica.org
Georgetown University's Climate Center primer on adaptation: http://www.georgetownclimate.org/adaptation
___
Seth Borenstein can be followed at http://twitter.com/borenbears
First of a two-part package on adapting to climate change. Tomorrow: Snapshots of what cities are doing around the world.
Source: http://news.yahoo.com/climate-talk-shifts-curbing-co2-adapting-130423769.html
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Retail sales surged 0.6 percent last month, on the strength of auto sales and building materials. Also this week, stock prices swing wildly as core wholesale prices suggest tame inflation and manufacturing slows. ?
By Schuyler Velasco,?Staff writer / June 15, 2013
EnlargeRetail sales go big:? Retail sales rose 0.6 percent in May and 4.3 percent since last year, beating analysts? predictions and stoking optimism for more accelerated economic growth going forward. Auto sales ruled the report, jumping 1.2 percent for the month. Excluding auto sales, retail sales rose only 0.3 percent. Building materials also gained 0.9 percent in a strong showing.
Skip to next paragraph Schuyler VelascoStaff writer/editor
Schuyler Velasco is a writer and editor for the Monitor's business desk.? She writes about consumer issues, sports, and the occasional sandwich.
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The data prompted Barclays Research to revise upward ? significantly ? its predictions for second-quarter gross domestic product: from a 1.1 percent annual rate to 1.8 percent.?
Wholesale prices rise sharply:?For the first time in three months, the index moved up, rising 0.5 percent from April to May, but it was due almost entirely to higher food and gasoline costs. Core prices, which exclude those two volatile categories rose only 0.1 percent. That suggests that underlying inflation is still tame, a key indicator the Federal Reserve is watching as it prepares to meet next week and review the economy and its own interest-rate policies. ? ??
Jobless claims fall: The number of people applying for initial unemployment benefits fell for the second week in a row last week, from 346,000 to 334,000 claims (a decline of 12,000), according to the Labor Department. It was the smallest number of applications since early May, and a hopeful sign that the job market is making further improvement. Job market performance will be a key factor in consumer spending and the growth of the US economy going forward, Josh Shapiro, chief US economist for MFR, Inc. in New York, wrote in an e-mailed analysis. ?On a fundamental basis, labor market conditions will be the key factor for the consumer, and evidence concerning job growth therefore will remain the paramount economic variable for some time.?
The stock market?s wild week: The US stock market has been on a roller coaster for the past week, with the Dow dropping over 100 points both Tuesday and Wednesday, then soaring on Thursday, and losing 105 points on Friday. The market gauge has swung more than 100 points in seven sessions over the past two weeks. The swings were felt abroad as well: Japan?s Nikkei Index plunged 6 percent Thursday.
The market volatility can be largely credited to uncertainty over central bank policies, and whether the Fed will allow short-term interest rates to climb in the coming months. In particular, bond prices have been falling in recent weeks over concerns that the Federal Reserve will soon scale back its stimulus efforts.?
Manufacturing goes flat: Total industrial production went unchanged in May, and manufacturing ticked up .01 percent. ?The weak numbers could be a signal that the US manufacturing sector is poised for a contraction, barring strong growth in June. ?Strong headwinds have made it difficult for the recovery to gain momentum,? IHS economist Erik Johnson wrote in an e-mailed analysis. ?The sequester will hurt growth through the end of the year, while slowing growth in emerging markets and a lengthy Eurozone recession have muted foreign demand. This is hurting manufacturing and prompting businesses to remain ultra-cautious about hiring and capital spending.?
Mortgage rates on the rise: ?The average interest rate for a 30-year fixed rate mortgage jumped to 3.98 percent this week, nearing the 4 percent mark for the first time in nearly a year and a half. The last time rates were over 4 percent was March 2012. ?Federal Reserve bond purchases have kept rates low during that period, and speculation that the Fed will end those purchases is pushing rates higher. Still, by historical standards, rates remain quite low.?
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When I first heard of a new coffee shop opening in Sarasota, I was only mildly interested. After all, how different can a cup of coffee truly be? But when I started to read online posts and reviews from people I know and respect, my interest in perq was definitely piqued. Could the process of brewing coffee really be made unique? What is all the fuss about? Is the coffee at perq truly superior?
In short, perq is at the forefront of the next generation of coffee brewing and consumption. It is different from traditional coffee bars and will change the way you prefer to consume coffee. It is an experience that, once tried, you will repeat again and again?dare I say, it?s addicting!
?
The perq experience
The coffee experience at perq differs from traditional coffee bars in a variety of ways. The first, and perhaps most obvious, is the selection of beans. The team at perq sources artisan-roasted, single-origin coffee beans which provide a variety of flavor profiles. Four small-lot varieties come with details on the coffee flavor palette, the farm and country of origin, and the processing, making ?Which bean?? your first decision in the perq experience.
The next step in your perq experience is picking your drink, which determines the methodology of the brewing process. Essentially there are a range of espresso, pour-over and press options, which yield various degrees of flavor extraction from the coffee beans. For the ultimate in barista control, perq uses a?Slayer?espresso machine, often referred to as the ?Ferrari of coffee machines.? Seem intimidating? Don?t be discouraged; the team at perq is very knowledgeable and will guide you through the process. Even though it might sound complicated, it is really easy and a great deal of fun picking your ?hand-made? coffee drink.
The third and final step to the perq experience is savoring the moment. Since each coffee is individually crafted, it takes a little time for the coffee to be delivered. This momentary break allows you time to soak in the hip surroundings of wood, chrome, green-colored accents, natural light, abundance of air plants and, of course, the ability to watch your coffee while it is being made. Once you hear your name called, your coffee is ready to be sipped and savored. Enjoy!
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Fad or Following?
Usually a great deal of buzz about a new opening means one of two things: The new place is truly buzz-worthy, a great place building a loyal following; or it is a fad?cool at first but not sustainable, usually eclipsed by the ?next great thing.?
Recent trends in food and dining such as farm-to-table, single-origin and artisan quality all support the concept behind the launch of perq. In fact, perq?s unique experience dovetails nicely into the craft beer, boutique winery, single-malt scotch, local small-batch distillery and beverage interests of foodies and aficionados alike.
With such a singular focus on coffee and its ultimate enjoyment, it would be easy for food to be an afterthought. Such is not the case at perq. Pastries and baked goods are freshly provisioned throughout the day by The Lollicake Queen (the husband runs perq, while the wife and sister-in-law run Lollicake) and lunchtime fare such as sandwiches and salads are provided by The Mozzarella Fella. The food at perq does not take a backseat to the coffee.
Although my first experience at perq was a good one, I must admit I couldn?t see myself coming to perq on a regular basis because it just was not convenient for me. That changed the next day when I suggested we go with friends to perq for an afternoon coffee ? and the next day when I suggested perq for breakfast. I think you get the picture: Every day is potentially a perq-perfect day.
perq coffee bar
1821 Hillview St.
Sarasota, FL 34239
941-955-8101
https://www.facebook.com/PerqCoffeeBar
Jack Littman-Quinn is a serial entrepreneur, writer, blogger, foodie and social media enthusiast, covering current trends in food, restaurants and dining in Sarasota. You can read more of Jack's restaurant reviews at www.srqreviews.com.
Source: http://www.thisweekinsarasota.com/piqued-by-perq-coffee-bar/
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There's no question that Nintendo is hurting these days, mostly owing to the lackluster reception for the Wii U. The company's Scott Moffitt is upbeat, however: he tells CNET that the Wii U should enjoy a 3DS-like sales renaissance this holiday now that games in bigger franchises, like Mario and Zelda, are on the way. Of course, the 3DS also had the advantage of a dramatic price drop -- but never you mind that. As for the handheld's own performance this year? Moffitt claims that the 3DS is the only dedicated console whose sales are still growing, and he expects the system to have its best holiday yet. His positions on the 3DS and Wii U strike us as optimistic when Nintendo is up against two major console launches and the ever-present threat of smartphone gaming, but the gaming giant has defied the odds more than once in its history.
Filed under: Gaming, Handhelds, Nintendo
Source: CNET
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